Trent University Graduate Thesis Collection

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    tula:etd
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    Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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    The Influence of nitrogen and sulfur on cadmium tolerance in Euglena gracilis: an RNA-Sequencing investigation

    Year: 2022, 2022
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Kennedy , Victoria, Thesis advisor (ths): Saville, Barry, Degree committee member (dgc): Emery, Neil, Degree committee member (dgc): Donaldson, Michael, Degree committee member (dgc): Farrow, Scott, Degree granting institution (dgg): Trent University
    Abstract: <p>Heavy metal pollution threatens human and ecosystem health. E. gracilis was investigated for its potential use in bioremediation due to its tolerance for heavy metals and ability to sequester them from the environment. E. gracilis can remove metals by producing metal binding compounds enriched in sulfur and nitrogen. In this thesis, E. gracilis cultures that were pretreated with elevated… more

    SARS-CoV-2 Protein-based Detection Using Localized Surface Plasmon Resonance

    Year: 2022, 2022
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Lewis, Tyra Marie, Thesis advisor (ths): Martic, Sanela, Degree committee member (dgc): Emery, Neil, Degree committee member (dgc): Saville, Barry, Degree granting institution (dgg): Trent University
    Abstract: <p>During the COVID-19 pandemic, nucleic acid and antibody-based testing methods were heavily relied upon, but can be costly, time-consuming and exhibit high false -negative and -positive rates. Thus, alternative strategies are needed. Viral antigens such as the SARS-CoV-2 spike (S) glycoprotein are critical in the function of the virus and useful as diagnostic biomarkers for viral… more

    Interactome study of the Giardia intestinalis nuclear localized cytochrome b5

    Year: 2022, 2022
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Batoff, Gordon William, Thesis advisor (ths): Yee, Janet, Degree committee member (dgc): Huber, Robert J, Degree committee member (dgc): Saville, Barry, Degree granting institution (dgg): Trent University
    Abstract: <p>Giardia intestinalis is a waterborne enteric parasite that lacks mitochondria and the capacity for heme biosynthesis. Despite this, Giardia encodes several heme proteins, including four cytochrome b5 isotypes (gCYTB5-I – IV) of unknown function. The aim of this thesis is to gain insight into the function of the Giardia cytochrome b5 isotype III (gCYTB5-III) that is found in the nucleus,… more