Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
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Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Functional Role of 97R in Host Cell Modulation during Frog Virus 3 Infection

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Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Bansal, Lakshika, Thesis advisor (ths): Brunetti, Craig R, Degree committee member (dgc): Tobin, Stephanie, Degree committee member (dgc): Yee, Janet, Degree granting institution (dgg): Trent University
Abstract: <p>Frog virus 3 (FV3) belongs to the genus Ranavirus within the Iridoviridae family.Its 105,903 base genome encodes 98 open reading frames (ORFs), including ORF 97R, a
putative apoptosis regulator sharing 31% structural similarity with the anti-apoptotic Bcl-
2 family protein, myeloid cell leukemia 1 (Mcl-1). 97R contains a BH1 domain,
implicated in apoptosis regulation, and a predicted C-… more