Trent University Graduate Thesis Collection

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    The Effect of Systemic Temozolomide on Learning, Emotional Behaviour, and Hippocampal Synaptic Plasticity: Implications for chemotherapy-induced cognitive impairment

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Blewett, Kaitlyn Alisha, Thesis advisor (ths): Fournier, Neil M, Degree committee member (dgc): Lehmann, Hugo, Degree committee member (dgc): Chan-Reynolds, Michael, Degree granting institution (dgg): Trent University
    Abstract: <p>ABSTRACT
    Patients who undergo chemotherapy often complain of a persistent 'brain fog' that can be present up to years after treatment ends. This fog is expressed as marked impairments in areas of learning, memory and mental health. As it stands, researchers have yet to determine the mechanism at fault for these impairments. The present experiment investigates if the… more