Trent University Graduate Thesis Collection

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tula:etd
Type
Collection
Language
eng
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1 item
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Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Electrochemical and Surface Analysis of Metal Ions and TDP-43 Protein Interactions

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Year: 2023, 2023
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Tabobondung, Meaghan O. F., Thesis advisor (ths): Martic, Sanela, Degree committee member (dgc): Emery, Neil, Degree committee member (dgc): Huber, Robert, Degree granting institution (dgg): Trent University
Abstract: <p>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive loss in function of motor neurons. Elevated levels of biologically important metal ions, such as copper (II) (Cu(II)), zinc (II) (Zn(II)) or iron (III) (Fe(III)), may contribute to the disease. Moreover, Cu(II) interactions with other proteins associated with ALS have been investigated;… more
Full Text: ELECTROCHEMICAL AND SURFACE ANALYSIS OF METAL IONS AND TDP-43 PROTEIN INTERACTIONS A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts and Science …