Year: 2021, 2021
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Cole, Ryan, Thesis advisor (ths): Slepkov, Aaron D, Degree committee member (dgc): Atkinson, Bill, Degree committee member (dgc): Vreugdenhil, Andrew, Degree committee member (dgc): Tamblyn, Isaac, Degree granting institution (dgg): Trent University Abstract: <p>Spectral-focusing-based coherent anti-Stokes Raman scattering (SF-CARS) microscopy is a powerful imaging technique that involves temporally and spectrally stretching ultrashort laser pulses and controlling their frequency-time characteristics. However, a broader and more detailed understanding of the frequency-time characteristics of the laser pulses and signals involved, how they are… more Full Text: FREQUENCY-TIME AND POLARIZATION CONSIDERATIONS IN SPECTRAL-FOCUSING-BASED CARS MICROSCOPY A THESIS SUBMITTED TO THE COMMITTEE ON GRADUATE STUDIES IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY IN THE FACULTY OF ARTS AND …
Year: 2021, 2021
Member of: Trent University Graduate Thesis Collection
Abstract: <p>The onset of neurodegenerative diseases such as Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS) are typically characterised by the aggregation of protein biomarkers into cytotoxic fibrils. Novel means of analysing these biomarkers are needed to expand the literature toward earlier diagnosis of these conditions. Electrochemical sensors could offer the sensitivity and… more Full Text: ELECTROCHEMICAL BIOSENSORS FOR NEURODEGENERATIVE DISEASE BIOMARKERS: INVESTIGATIONS INTO THE ORIGIN AND DIAGNOSIS OF ALZHEIMER’S DISEASE AND AMYOTROPHIC LATERAL SCLEROSIS A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of …
