Trent University Graduate Thesis Collection

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    Electrochemical Biosensors for Neurodegenerative Disease Biomarkers: Investigations into the origin and diagnosis of Alzheimer's disease and amyotrophic lateral sclerosis

    Year: 2021, 2021
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Wallace, William, Thesis advisor (ths): Martic, Sanela, Degree committee member (dgc): Rafferty, Steven, Degree committee member (dgc): Vreugdenhil, Andrew, Degree granting institution (dgg): Trent University
    Abstract: <p>The onset of neurodegenerative diseases such as Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS) are typically characterised by the aggregation of protein biomarkers into cytotoxic fibrils. Novel means of analysing these biomarkers are needed to expand the literature toward earlier diagnosis of these conditions. Electrochemical sensors could offer the sensitivity and… more