Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Assessing Cytokinin Inhibition of frog virus 3 Replication and Changes in Nuclear Morphology

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Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Prevost, Galair, Thesis advisor (ths): Brunetti, Craig, Degree committee member (dgc): Emery, Neil R.J., Degree committee member (dgc): Huber, Robert J., Degree granting institution (dgg): Trent University
Abstract: <p>Cytokinins (CKs) are adenine derivative molecules that are present in all kingdoms of life. CKs are known to have a role in cell growth and development in plants. However, the role of CKs in vertebrate systems is not well understood. Frog virus 3 (FV3) is a type species of the Iridioviridae family, genus Ranavirus. FV3 is a major contributor to the amphibian population decline in North… more

The role of Cln5 in autophagy, using a Dictyostelium discoideum model of Batten disease

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Year: 2020, 2020
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): McLaren, Meagan, Thesis advisor (ths): Huber, Robert J., Degree committee member (dgc): Kapron, Carolyn, Degree committee member (dgc): Brunetti, Craig, Degree granting institution (dgg): Trent University
Abstract: <p>This thesis investigated the role of the neuronal ceroid lipofuscinosis protein, Cln5, during autophagy. This was accomplished by performing well-established assays in a Dictyostelium cln5 knockout model (cln5-). In this study, cln5- cells displayed a reduced maximum cell density during growth and impaired cell proliferation in autophagy-stimulating media. cln5- cells had an increased… more
Full Text: The role of Cln5 in autophagy, using a Dictyostelium discoideum model of Batten disease A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for Degree of Master of Science in the Faculty of Arts and Science …