Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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The first confirmation that Insects synthesize Cytokinins: Cytokinin metabolite and gene expression profiling following functional manipulations of tRNA IPT genes in Drosophila melanogaster

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Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Andreas, Peter Frank, Thesis advisor (ths): Emery, R.J. N, Degree committee member (dgc): Beresford, David V, Degree committee member (dgc): Kisiala, Anna B, Degree committee member (dgc): Morrison, Erin N, Degree granting institution (dgg): Trent University
Abstract: <p>Using Drosophila deficiency (Df) and Over Expression (OE) (GAL4/UAS&gt;dCas9-VPR; sgRNA) gene systems, it was demonstrated that Dmel_CG31381 and Dmel_CG11089 are functional tRNA isopentenyltransferase (EC 2.5.1.8) genes (tRNA IPT1 and IPT2) critical to the first committed step in insect cytokinin biosynthesis. IPT Df mutants showed significant decreases in total CK levels and IPT1/… more

Mfsd8 regulates growth and multicellular development in Dictyostelium discoideum

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Year: 2022, 2022
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Yap, Shyong Quan, Thesis advisor (ths): Huber, Robert J, Degree committee member (dgc): Kapron, Carolyn, Degree committee member (dgc): Morrison, Erin N, Degree granting institution (dgg): Trent University
Abstract: <p>The neuronal ceroid lipofuscinoses (NCLs), commonly known as Batten disease, are a family of inherited neurodegenerative lysosomal storage disorders. CLN7 disease is a subtype of NCL that is caused by mutations in the MFSD8 gene. MFSD8 encodes a lysosomal transmembrane protein that is predicted to play a role in transporting small substrates across membranes. However, little is known… more
Full Text: Mfsd8 regulates growth and multicellular development in Dictyostelium discoideum A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for Degree of Master of Science in the Faculty of Arts and Science TRENT …