Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Abstract: <p>Frog virus 3 (FV3) belongs to the genus Ranavirus within the Iridoviridae family.Its 105,903 base genome encodes 98 open reading frames (ORFs), including ORF 97R, a
putative apoptosis regulator sharing 31% structural similarity with the anti-apoptotic Bcl-
2 family protein, myeloid cell leukemia 1 (Mcl-1). 97R contains a BH1 domain,
implicated in apoptosis regulation, and a predicted C-… more Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Knight, Caitlyn, Thesis advisor (ths): Kapron, Carolyn, Degree committee member (dgc): Tobin, Stephanie, Degree committee member (dgc): Huber, Robert, Degree committee member (dgc): West, Sarah, Degree granting institution (dgg): Trent University Abstract: <p>Cadmium is a toxic metal that has detrimental effects on blood vessel development and function. To examine the effect of varying concentrations of cadmium on angiogenesis, two in vitro assays were used. First, developing yolk sac blood vessels were studied in gestation day 8 mouse embryos exposed to medium alone, 1.25, or 1.75 μM cadmium chloride (CdCl2). Embryos exposed to 1.25 μM… more Full Text: Concentration-Dependent Effects of Cadmium on Mouse Angiogenesis In Vitro A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Science in the Faculty of Arts and Science TRENT UNIVERSITY …
Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Knight, Caitlyn, Thesis advisor (ths): Kapron, Carolyn, Degree committee member (dgc): Tobin, Stephanie, Degree committee member (dgc): Huber, Robert, Degree committee member (dgc): West, Sarah, Degree granting institution (dgg): Trent University Abstract: <p>Cadmium is a toxic metal that has detrimental effects on blood vessel development and function. To examine the effect of varying concentrations of cadmium on angiogenesis, two in vitro assays were used. First, developing yolk sac blood vessels were studied in gestation day 8 mouse embryos exposed to medium alone, 1.25, or 1.75 μM cadmium chloride (CdCl2). Embryos exposed to 1.25 μM… more
