Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
Displaying 1 - 4 of 4

Results per page

Displaying 1 - 4 of 4

An in vitro characterization of the novel binding properties of the Giardia TATA-binding protein

Freitag_trentu_0513N_11279-Thumbnail Image.png
Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Freitag, Kieran, Thesis advisor (ths): Yee, Janet, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Huber, Robert, Degree granting institution (dgg): Trent University
Abstract: <p>The TATA-binding protein (TBP) is a key regulator of eukaryotic transcription initiation. The TBP homolog from Giardia intestinalis (gTBP) is highly divergent among all TBPs; notably lacking three of the four phenylalanine residues to unwind double- stranded DNA. I show that gTBP preferentially binds to single-stranded DNA (ssDNA) in two modes based on sequence and protein concentration… more

Investigation of the Oxidative Activity of Giardia Flavohemoglobins

Decorso_trentu_0513N_11293-Thumbnail Image.png
Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Decorso, Isabelle, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
Abstract: <p>Flavohemoglobins are enzymes primarily implicated in nitrosative stress due to their high nitric oxide (NO) dioxygenase activity and transcriptional upregulation in response to NO. Giardia intestinalis assemblages A, B, and E possess flavohemoglobins (gFlHb) that may function beyond their NO dioxygenase activity, potentially contributing to oxidative stress regulation, as transcriptional… more

Transcriptome Changes and the Role of RNA Helicases in Ustilago maydis During Teliospore Dormancy and Germination

Seto_trentu_0513D_11346-Thumbnail Image.png
Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Seto, Amanda, Thesis advisor (ths): Saville, Barry J, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Yee, Janet, Degree granting institution (dgg): Trent University
Abstract: <p>Crop losses due to pathogens, pests, and weeds account for 20–40% of global production, with fungal pathogens responsible for the most significant yield reductions and economic impact. The diseases caused by fungi spread through dormant spores, which protect its genetic material under adverse conditions. Dormancy is maintained until favorable germination conditions are met. Despite their… more