Trent University Graduate Thesis Collection

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    Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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    Altered Hippocampal Regulation of Immediate Early Genes after Pentylenetetrazol-Induced Seizures

    Year: 2019, 2019
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Kalinina, Alena, Thesis advisor (ths): Fournier, Neil M, Degree committee member (dgc): Lehmann, Hugo, Degree granting institution (dgg): Trent University
    Abstract: <p>Seizures induce long-term changes in gene expression in the hippocampus. Experimental evidence has demonstrated a significant effect of epileptic activity on the activity of neurons that participate in complex cognitive and behavioural processes. The present series of experiments involving kindling with subconvulsive doses of PTZ demonstrates a link between seizures and altered immediate… more