Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Displaying 1 - 4 of 4

Context Fear Memory: Escaping the Hippocampus

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Year: 2019, 2019
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Kishun, Swarsattie, Thesis advisor (ths): Lehmann, Hugo, Degree committee member (dgc): Fournier, Neil, Degree granting institution (dgg): Trent University
Abstract: <p>Distributing contextual fear episodes makes the memory become HPC-independent, meaning increasingly reliant on non-HPC memory structures. It is unclear, however, whether distribution of the conditioning episodes alone is sufficient or whether a combination of distribution and high conditioning saliency is necessary to make the memory become HPC-independent. To resolve this issue, rats… more
Full Text: i CONTEXT FEAR MEMORY: ESCAPING THE HIPPOCAMPUS A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts and Science TRENT UNIVERSITY Peterborough, …

Assessing the Clinical Usefulness of Three Tablet-Based Visuomotor Tasks to Evaluate Closed Head Injury

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Year: 2019, 2019
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Livermore, Jasmine, Thesis advisor (ths): Brown, Liana E, Thesis advisor (ths): Lehmann, Hugo, Degree granting institution (dgg): Trent University
Abstract: <p>Evidence suggests that visuomotor system behaviour may be more sensitive to the prolonged effects of mild brain injuries than neuropsychological tests. We evaluated whether participants with a mild closed head injury (CHI) would show lingering visuomotor deficits, but not cognitive deficits, up to three years post-injury compared to participants with an orthopaedic injury and healthy… more
Full Text: Assessing the Clinical Usefulness of Three Tablet-Based Visuomotor Tasks to Evaluate Closed Head Injury A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty …

Altered Hippocampal Regulation of Immediate Early Genes after Pentylenetetrazol-Induced Seizures

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Year: 2019, 2019
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Kalinina, Alena, Thesis advisor (ths): Fournier, Neil M, Degree committee member (dgc): Lehmann, Hugo, Degree granting institution (dgg): Trent University
Abstract: <p>Seizures induce long-term changes in gene expression in the hippocampus. Experimental evidence has demonstrated a significant effect of epileptic activity on the activity of neurons that participate in complex cognitive and behavioural processes. The present series of experiments involving kindling with subconvulsive doses of PTZ demonstrates a link between seizures and altered immediate… more
Full Text: ALTERED HIPPOCAMPAL REGULATION OF IMMEDIATE EARLY GENES AFTER PENTYLENETETRAZOL-INDUCED SEIZURES A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts …

Impaired contextual fear discrimination learning after long-term amygdala kindling

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Year: 2019, 2019
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Francis, Travis James, Thesis advisor (ths): Fournier, Neil M, Degree committee member (dgc): Lehmann, Hugo, Degree committee member (dgc): Melvin, Neal, Degree granting institution (dgg): Trent University
Abstract: <p>Cognitive impairments, such as memory loss, are a frequent and devastating co-morbidity associated with epilepsy. The neurobiological mechanisms through which recurrent seizures induce cognitive impairments are not well understood. New neurons born after seizures develop abnormal morphological and functional characteristics that promote network hyperexcitability and hippocampal… more
Full Text: Impaired contextual fear discrimination learning after long-term amygdala kindling A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts and Science …