Trent University Graduate Thesis Collection

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tula:etd

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Collection

Language

eng

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1 item

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Impaired contextual fear discrimination learning after long-term amygdala kindling

Year: 2019, 2019

Member of: Trent University Graduate Thesis Collection

Name(s): Creator (cre): Francis, Travis James, Thesis advisor (ths): Fournier, Neil M, Degree committee member (dgc): Lehmann, Hugo, Degree committee member (dgc): Melvin, Neal, Degree granting institution (dgg): Trent University

Abstract: <p>Cognitive impairments, such as memory loss, are a frequent and devastating co-morbidity associated with epilepsy. The neurobiological mechanisms through which recurrent seizures induce cognitive impairments are not well understood. New neurons born after seizures develop abnormal morphological and functional characteristics that promote network hyperexcitability and hippocampal… more

Full Text: Impaired contextual fear discrimination learning after long-term amygdala kindling A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts and Science …