Trent University Graduate Thesis Collection

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    Differential expression of cytochrome b5s in Giardia intestinalis during nitrosative stress and encystation

    Year: 2020, 2020
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Mowat, Kaitlyn, Thesis advisor (ths): Yee, Janet, Degree committee member (dgc): Huber, Robert, Degree committee member (dgc): Saville, Barry, Degree granting institution (dgg): Trent University
    Abstract: <p>The waterborne protozoan Giardia intestinalis cycles between the environmentally-resistant and infectious cyst and the metabolically-active trophozoite that adheres to the epithelial lining of the small intestine. Adhesion can trigger the innate immune response in epithelial cells, including the synthesis of the free radical nitric oxide (NO) that inhibits cell proliferation and… more