Trent University Graduate Thesis Collection

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    tula:etd
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    1 item
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    Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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    Stress Axis Function and Regulation in New World Flying Squirrels: An Assessment of Acute Stress Response, Negative Feedback, and the Role of Corticosteroid-binding Globulin

    Year: 2017, 2017
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Desantis, Lanna Marie, Thesis advisor (ths): Bowman, Jeff, Thesis advisor (ths): Burness, Gary, Degree committee member (dgc): Rafferty, Steven, Degree committee member (dgc): Wilson, Paul, Degree committee member (dgc): Boonstra, Rudy, Degree committee member (dgc): Vijayan, Mathilakath M, Degree granting institution (dgg): Trent University
    Abstract: <p>Across vertebrate taxa, the hypothalamic-pituitary-adrenal axis (or the stress axis) is highly conserved, and is central to vertebrate survival because it allows appropriate responses to psychological stressors. Habitat shapes successful physiological and ecological strategies, and to appreciate how individual species respond to stressors in their environment, it is essential to have a… more

    Flavohemoglobin expression in Giardia intestinalis exposed to nitrosative stress

    Year: 2017, 2017
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Teghtmeyer, Megan R, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Yee, Janet, Degree granting institution (dgg): Trent University
    Abstract: <p>The parasitic protist Giardia intestinalis lacks most heme proteins yet encodes a flavohemoglobin (gFlHb) that converts nitric oxide to nitrate and likely protects the cell from nitrosative stress. In this work an antibody raised against gFlHb was used to examine both changes in gFlHb expression levels and intracellular localization in Giardia in response to nitrosative stress. Giardia… more

    Interactome Study of Giardia Intestinalis Cytochromes B5

    Year: 2017, 2017
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Dayer, Guillem Sébastien, Thesis advisor (ths): Yee, Janet, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Saville, Barry, Degree granting institution (dgg): Trent University
    Abstract: <p>Giardia intestinalis is an anaerobic protozoan that lacks common eukaryotic heme-dependent respiratory complexes and does not encode any proteins involved in heme biosynthesis. Nevertheless, the parasite encodes several hemeproteins, including three members of the Type II cytochrome b5 sub-group of electron transport proteins found in anaerobic protist and amitochondriate organisms.… more