Year: 2017, 2017
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Dayer, Guillem Sébastien, Thesis advisor (ths): Yee, Janet, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Saville, Barry, Degree granting institution (dgg): Trent University Abstract: <p>Giardia intestinalis is an anaerobic protozoan that lacks common eukaryotic heme-dependent respiratory complexes and does not encode any proteins involved in heme biosynthesis. Nevertheless, the parasite encodes several hemeproteins, including three members of the Type II cytochrome b5 sub-group of electron transport proteins found in anaerobic protist and amitochondriate organisms.… more Full Text: INTERACTOME STUDY OF GIARDIA INTESTINALIS CYTOCHROMES B5 TRENT UNIVERSITY Peterborough, Ontario, Canada © Copyright by Guillem Dayer 2017 Environmental and Life Sciences Ph.D. Graduate Program May 2017 ABSTRACT Interactome study of Giardia intestinalis …
Year: 2017, 2017
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Desantis, Lanna Marie, Thesis advisor (ths): Bowman, Jeff, Thesis advisor (ths): Burness, Gary, Degree committee member (dgc): Rafferty, Steven, Degree committee member (dgc): Wilson, Paul, Degree committee member (dgc): Boonstra, Rudy, Degree committee member (dgc): Vijayan, Mathilakath M, Degree granting institution (dgg): Trent University Abstract: <p>Across vertebrate taxa, the hypothalamic-pituitary-adrenal axis (or the stress axis) is highly conserved, and is central to vertebrate survival because it allows appropriate responses to psychological stressors. Habitat shapes successful physiological and ecological strategies, and to appreciate how individual species respond to stressors in their environment, it is essential to have a… more Full Text: STRESS AXIS FUNCTION AND REGULATION IN NEW WORLD FLYING SQUIRRELS: AN ASSESSMENT OF ACUTE STRESS RESPONSE, NEGATIVE FEEDBACK, AND THE ROLE OF CORTICOSTEROID-BINDING GLOBULIN A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of …
Year: 2017, 2017
Member of: Trent University Graduate Thesis Collection
Abstract: <p>The parasitic protist Giardia intestinalis lacks most heme proteins yet encodes a flavohemoglobin (gFlHb) that converts nitric oxide to nitrate and likely protects the cell from nitrosative stress. In this work an antibody raised against gFlHb was used to examine both changes in gFlHb expression levels and intracellular localization in Giardia in response to nitrosative stress. Giardia… more Full Text: FLAVOHEMOGLOBIN EXPRESSION IN GIARIDA INTESTINALIS EXPOSED TO NITROSATIVE STRESS A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts and Science …