Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Fungal pathogen emergence: an Ustilago maydis x Sporisorium reilianum model

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Year: 2021, 2021
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Storfie, Emilee, Thesis advisor (ths): Saville, Barry, Degree committee member (dgc): Donaldson, Michael, Degree committee member (dgc): Huber, Robert, Degree granting institution (dgg): Trent University
Abstract: <p>The emergence of fungal hybrid pathogens threatens sustainable crop production worldwide. To investigate hybridization, the related smut fungi, Ustilago maydis and Sporisorium reilianum, were selected because they infect a common host (Zea mays), can hybridize, and tools are available for their analysis. Hybrid dikaryons exhibited filamentous growth on plates but reduced virulence and… more
Full Text: Fungal pathogen emergence: an Ustilago maydis x Sporisorium reilianum model A thesis submitted to the Committee of Graduate Studies in partial fulfillment of the requirements for the degree of Master of Science in the faculty of Arts and Science TRENT …

Immunotherapies Targeting the Amyotrophic Lateral Sclerosis-Associated Protein TDP-43

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Year: 2021, 2021
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Esposto, Josephine, Thesis advisor (ths): Martic, Sanela, Degree committee member (dgc): Rafferty, Steven, Degree committee member (dgc): Huber, Robert, Degree granting institution (dgg): Trent University
Abstract: <p>Transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) pathology, including fibrillar aggregates and mutations, develops in amyotrophic lateral sclerosis (ALS) and is characterized by hyperphosphorylation and aggregation patterns, a mechanism largely understudied. In addition, ALS remains without a cure. Herein, in vitro aggregation of phosphorylated TDP-43 was explored, and… more
Full Text: IMMUNOTHERAPIES TARGETING THE AMYOTROPHIC LATERAL SCLEROSIS-ASSOCIATED PROTEIN TDP-43 A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts and …

Expression of Giardia intestinalis flavoenzyme GiOR-1 and characterization of its electron transfer properties

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Year: 2021, 2021
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Villeneuve, Tiffany C., Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Huber, Robert, Degree committee member (dgc): Brunetti, Craig, Degree granting institution (dgg): Trent University
Abstract: <p>Giardia intestinalis possesses four isotypes of cytochrome b5 (gCYTB-I-IV) that differ from their mammalian counterparts, suggesting different functions in this protozoan parasite. Although the recently discovered Giardia flavoenzyme, GiOR-1, reduces these cytochromes, its properties have not been thoroughly studied, owing to the difficulty in its expression. Here I describe successful… more
Full Text: Expression of Giardia intestinalis flavoenzyme GiOR-1 and characterization of its electron transfer properties A thesis submitted to the Committee on Graduate Studies in partial fulfillment of the requirements for the degree of Master of Science in the …