Trent University Graduate Thesis Collection

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    Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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    Rapid Assays to Test for Flavohemoglobin Inhibitors

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Henao, Elias, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
    Abstract: <p>Giardia intestinalis is a parasitic protozoan that possesses a flavohemoglobin (gFlHb), an enzyme that plays a role in the detoxification of reactive nitrogen species (RNS) and reactive oxygen species (ROS) via its nitric oxide dioxygenase (NOD) activity as well as its NADH-oxidase activity. This enzyme is a potential target for imidazole-based antigiardial drugs that act as ligands of… more
    Full Text: Rapid Assays to Test for Flavohemoglobin Inhibitors A thesis submitted to the Committee of Graduate Studies in partial fulfillment of the requirements for the degree of Master of Science in the Faculty of Arts and Science Trent University Peterborough, …

    Rapid Assays to Test for Flavohemoglobin Inhibitors

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Henao, Elias, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
    Abstract: <p>Giardia intestinalis is a parasitic protozoan that possesses a flavohemoglobin (gFlHb), an enzyme that plays a role in the detoxification of reactive nitrogen species (RNS) and reactive oxygen species (ROS) via its nitric oxide dioxygenase (NOD) activity as well as its NADH-oxidase activity. This enzyme is a potential target for imidazole-based antigiardial drugs that act as ligands of… more

    Assessing Cytokinin Inhibition of frog virus 3 Replication and Changes in Nuclear Morphology

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Prevost, Galair, Thesis advisor (ths): Brunetti, Craig, Degree committee member (dgc): Emery, Neil R.J., Degree committee member (dgc): Huber, Robert J., Degree granting institution (dgg): Trent University
    Abstract: <p>Cytokinins (CKs) are adenine derivative molecules that are present in all kingdoms of life. CKs are known to have a role in cell growth and development in plants. However, the role of CKs in vertebrate systems is not well understood. Frog virus 3 (FV3) is a type species of the Iridioviridae family, genus Ranavirus. FV3 is a major contributor to the amphibian population decline in North… more