Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Andreas, Peter Frank, Thesis advisor (ths): Emery, R.J. N, Degree committee member (dgc): Beresford, David V, Degree committee member (dgc): Kisiala, Anna B, Degree committee member (dgc): Morrison, Erin N, Degree granting institution (dgg): Trent University Abstract: <p>Using Drosophila deficiency (Df) and Over Expression (OE) (GAL4/UAS>dCas9-VPR; sgRNA) gene systems, it was demonstrated that Dmel_CG31381 and Dmel_CG11089 are functional tRNA isopentenyltransferase (EC 2.5.1.8) genes (tRNA IPT1 and IPT2) critical to the first committed step in insect cytokinin biosynthesis. IPT Df mutants showed significant decreases in total CK levels and IPT1/… more Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Abstract: <p>Giardia intestinalis is the causative agent of a diarrheal disease in mammals, but the mechanisms of disease pathogenesis are unclear. While proteins secreted by Giardia affect the host cells, the potential of hormone secretion has not been investigated to date. Cytokinins (CKs) are classified as phytohormones, but little is known about their role beyond plants. Mass spectrometry-based… more Full Text: The effect of cytokinins on the metabolite secretome of Giardia intestinalis during trophozoite growth, nutrient deprivation, and encystation A thesis submitted to the Committee of Graduate Studies in partial fulfillment of the requirements for the degree …
Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Abstract: <p>Giardia intestinalis is the causative agent of a diarrheal disease in mammals, but the mechanisms of disease pathogenesis are unclear. While proteins secreted by Giardia affect the host cells, the potential of hormone secretion has not been investigated to date. Cytokinins (CKs) are classified as phytohormones, but little is known about their role beyond plants. Mass spectrometry-based… more
