Trent University Graduate Thesis Collection

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tula:etd
Type
Collection
Language
eng
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1 item
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Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Rapid Assays to Test for Flavohemoglobin Inhibitors

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Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Henao, Elias, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
Abstract: <p>Giardia intestinalis is a parasitic protozoan that possesses a flavohemoglobin (gFlHb), an enzyme that plays a role in the detoxification of reactive nitrogen species (RNS) and reactive oxygen species (ROS) via its nitric oxide dioxygenase (NOD) activity as well as its NADH-oxidase activity. This enzyme is a potential target for imidazole-based antigiardial drugs that act as ligands of… more
Full Text: Rapid Assays to Test for Flavohemoglobin Inhibitors A thesis submitted to the Committee of Graduate Studies in partial fulfillment of the requirements for the degree of Master of Science in the Faculty of Arts and Science Trent University Peterborough, …