Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Changes in Pain Sensitivity in the Amygdala Kindling Model of Temporal Lobe Epilepsy

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Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Xiao, Evana, Thesis advisor (ths): Fournier, Neil M, Degree committee member (dgc): Paquette, Sebastien, Degree committee member (dgc): Dotta, Blake, Degree granting institution (dgg): Trent University
Abstract: <p>Pain conditions occur at an increasing rate alongside people with temporal lobe epilepsy (TLE) and can include chronic headaches, migraines, and neuropathic pain. In order to begin to understand the concurrence, this experiment aimed to investigate the effect of long-term amygdala kindling, a model of TLE, on the affective and nociceptive components of pain in rats. Formalin-induced… more

A Novel Approach to Investigating Stress-Pain Hypersensitivity

Johnston_trentu_0513N_11257-Thumbnail Image.png
Year: 2025, 2025
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Johnston, Kirkland, Thesis advisor (ths): Fournier, Neil M, Degree committee member (dgc): Smith-Chant, Brenda, Degree committee member (dgc): Tobin, Stephanie W, Degree granting institution (dgg): Trent University
Abstract: <p>It is well known that pain can heighten sensitivity to stimuli that signal threat in most species. In rodents, exposure to predator odor, such as 2,5-dihydro-2,4,5-trimethylthiazoline (TMT), induces anxiety and alters pain sensitivity. This study explored the effect of predator odor stress on mechanical pain sensitivity in a rat model of acute inflammatory pain induced by suboptimal… more