Trent University Graduate Thesis Collection

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tula:etd
Type
Collection
Language
eng
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1 item
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Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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Advancements and Challenges in Ciguatoxin Detection: Developing a High- Resolution Mass Spectrometric Method for the Identification of P-CTX-3B

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Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Prytulka, Natasha Grace, Thesis advisor (ths): Hintelmann, Holger, Thesis advisor (ths): Stock, Naomi, Degree committee member (dgc): Metcalfe, Chris, Degree granting institution (dgg): Trent University
Abstract: <p>The detection of ciguatoxins (CTXs) in biological samples is challenging due to their low concentrations, the presence of various congeners, and the absence of standardized methods. This study uses high resolution mass spectrometry (HRMS) with P-CTX-3B as a reference standard. The protonated molecules ([M+H]+) were most prevalent, especially when acetonitrile/water was utilized,… more
Full Text: Advancements and Challenges in Ciguatoxin Detection: Developing a HighResolution Mass Spectrometric Method for the Identification of P-CTX-3B A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree …