Trent University Graduate Thesis Collection

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    Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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    Advancements and Challenges in Ciguatoxin Detection: Developing a High- Resolution Mass Spectrometric Method for the Identification of P-CTX-3B

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Prytulka, Natasha Grace, Thesis advisor (ths): Hintelmann, Holger, Thesis advisor (ths): Stock, Naomi, Degree committee member (dgc): Metcalfe, Chris, Degree granting institution (dgg): Trent University
    Abstract: <p>The detection of ciguatoxins (CTXs) in biological samples is challenging due to their low concentrations, the presence of various congeners, and the absence of standardized methods. This study uses high resolution mass spectrometry (HRMS) with P-CTX-3B as a reference standard. The protonated molecules ([M+H]+) were most prevalent, especially when acetonitrile/water was utilized,… more

    The design of DNA-containing biomaterials for forensic science

    Year: 2023, 2023
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Orr, Amanda, Thesis advisor (ths): Stotesbury, Theresa, Thesis advisor (ths): Wilson, Paul, Degree committee member (dgc): Stotesbury, Theresa, Degree committee member (dgc): Wilson, Paul, Degree committee member (dgc): Stock, Naomi, Degree granting institution (dgg): Trent University
    Abstract: <p>Access to human blood for forensic research and training in bloodstain pattern analysis (BPA) can be difficult due to many ethical, safety and cost concerns. Mammalian blood alternatives can be sourced, especially from local and willing abattoirs, but some concerns remain, and the added difficulties of high variation and species-specific differences in cellular components pose other… more

    Electrochemical versus Chemical Oxidation of Bulky Phenols: 2,6-diphenylphenol and 2,2-dihydroxybiphenol

    Year: 2023, 2023
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Gao, Stephanie, Thesis advisor (ths): Martic, Sanela, Degree committee member (dgc): Shetranjiwalla-Merchant, Shegufta, Degree committee member (dgc): Stock, Naomi, Degree granting institution (dgg): Trent University
    Abstract: <p>Phenolic compounds are used in industry, such as agriculture and biotechnology, and inevitably end up in our environment. These compounds may serve as a phenolic precursor to produce raw materials for a wide range of applications. Chemical oxidation has been the common synthetic pathway to oxidize phenols and related compounds. However, traditional chemical approaches suffer from use of… more

    Fingerprinting of dissolved organic matter and copper ligands in the Canadian Arctic and North Pacific Ocean

    Year: 2019, 2019
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Durrett, Victoria, Thesis advisor (ths): Gueguen, Celine, Degree committee member (dgc): Stock, Naomi, Degree committee member (dgc): Stotesbury, Theresa, Degree granting institution (dgg): Trent University
    Abstract: <p>Dissolved organic matter (DOM) in oceans provides nutrients and ultraviolet radiation protection to microbes. Some DOM compounds can chelate with metals, including copper, controlling their transport and bioavailability in marine systems. As copper functions as both a nutrient and toxicant, studies into the chemical structures of Cu-ligands is important, however currently limited. In… more

    cis-Cytokinins from the tRNA-degradation pathway impact the phenotype and metabolome of Arabidopsis thaliana: evidence from AtIPT2 and AtIPT9 null mutants

    Year: 2019, 2019
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Butler, Cody Wade, Thesis advisor (ths): Emery, Neil, Degree committee member (dgc): Stock, Naomi, Degree committee member (dgc): Ellis, David, Degree granting institution (dgg): Trent University
    Abstract: <p>Cis-isomers of the cytokinin plant hormone family are thought to have low activity or impact on plant growth and development. Mutants with independent silencing of the pathway leading to cis-CK (cis-cytokinin) were investigated at the phenotype and metabolite levels. Phenotypic deviations were noted in trichome development, fresh weight, rosette diameter, number of non-rosette leaves,… more

    Expression and characterization of cytochrome b5 from Giardia lamblia

    Year: 2015, 2015
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Alam, Samiah Ashraf, Thesis advisor (ths): Rafferty, Steven P, Degree committee member (dgc): Yee, Janet, Degree committee member (dgc): Stock, Naomi, Degree granting institution (dgg): Trent University
    Abstract: <p>Giardia lamblia is an intestinal parasite found globally in freshwater systems that is responsible for endemic outbreaks of infectious diarrhea. As a unicellular parasite that lacks mitochondria, a respiratory chain and lives in the anaerobic environment of its host's intestine, Giardia was assumed for decades to lack heme proteins. However, its genome encodes several putative heme… more

    The Effect of Water Surface Simulated Rain Drop Impacts on Water to Air Chemical Transfers of Perfluorinated Carboxylic Acids (PFCAs)

    Year: 2014, 2014
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): McInnes, Mark Andrew, Thesis advisor (ths): Ellis, David A, Degree committee member (dgc): Thompson, Matthew, Degree committee member (dgc): Gueguen, Celine, Degree committee member (dgc): Stock, Naomi, Degree granting institution (dgg): Trent University
    Abstract: <p>Perfluorinated carboxylic acids (PFCAs) are anthropogenic environmentally ubiquitous surfactants that tend to concentrate on water surfaces. This investigation looked at the effect of simulated rain on the atmospheric concentration of a suite of PFCAs (C2 - C12) above the bulk water system. Increased air concentrations of all PFCAs were detected during simulated rain events. Long chain… more