Trent University Graduate Thesis Collection

Item Description
Identifier
tula:etd
Type
Collection
Language
eng
Extent
1 item
Rights
Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
Displaying 1 - 1 of 1

Results per page

Displaying 1 - 1 of 1

Insights from Dictyostelium: Examining the role of cellular stress in Batten disease

23243-Thumbnail Image.png
Year: 2024, 2024
Member of: Trent University Graduate Thesis Collection
Name(s): Creator (cre): Thanabalasingam, Aruban, Thesis advisor (ths): Huber, Robert J, Degree committee member (dgc): Yee, Janet, Degree committee member (dgc): Donaldson, Micheal, Degree granting institution (dgg): Trent University
Abstract: <p>The neuronal ceroid lipofuscinoses (NCLs), commonly known as Batten disease, are a family of fatal neurodegenerative disorders that primarily affect children. Several subtypes of NCLs have been reported, each being caused by a mutation in a distinct ceroid lipofuscinosis neuronal (CLN) gene; this results in aberrant lysosome function and the accumulation of lipoprotein aggregates (known… more
Full Text: Insights from Dictyostelium: Examining the role of cellular stress in Batten disease A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for Degree of Master of Science in the Faculty of Arts and Science …