Trent University Graduate Thesis Collection

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    Expression of Giardia intestinalis flavoenzyme GiOR-1 and characterization of its electron transfer properties

    Year: 2021, 2021
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Villeneuve, Tiffany C., Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Huber, Robert, Degree committee member (dgc): Brunetti, Craig, Degree granting institution (dgg): Trent University
    Abstract: <p>Giardia intestinalis possesses four isotypes of cytochrome b5 (gCYTB-I-IV) that differ from their mammalian counterparts, suggesting different functions in this protozoan parasite. Although the recently discovered Giardia flavoenzyme, GiOR-1, reduces these cytochromes, its properties have not been thoroughly studied, owing to the difficulty in its expression. Here I describe successful… more