Modelling Cholera Transmission with Delayed Bacterial Shedding and Disinfection Control

Document
Abstract

This study focuses on the world dynamics of a cholera model that includes delayed bacterial shedding and water disinfection. From the method of the next generation matrix, a basic reproduction number is found that sets a threshold of disease persistence. It is shown that the disease disappears if $R_0<1$, which means that the disease-free equilibrium is globally asymptotically stable. The system is not destabilized by the delay, which leads to periodic oscillations. The numerical simulations validate the theoretical analysis, which illustrates the importance of delay and disinfection in cholera prevention and control.

Author Keywords: Basic reproduction number, Cholera, Delay differential equations, Disinfection, Lyapunov function, Stability analysis

    Item Description
    Type
    Contributors
    Creator (cre): Urmee, Farjana Zaman
    Thesis advisor (ths): Abdella, Kenzu
    Thesis advisor (ths): Wang, Xiaoying
    Degree committee member (dgc): Parker, James
    Degree committee member (dgc): Shu, Hongying
    Degree granting institution (dgg): Trent University
    Date Issued
    2025
    Date (Unspecified)
    2025
    Place Published
    Peterborough, ON
    Language
    Extent
    70 pages
    Rights
    Copyright is held by the author, with all rights reserved, unless otherwise noted.
    Subject (Topical)
    Local Identifier
    TC-OPET-32171274
    Publisher
    Trent University
    Degree