Trent University Graduate Thesis Collection

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    Copyright for all items in the Trent University Graduate Thesis Collection is held by the author, with all rights reserved, unless otherwise noted.
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    Performance of Time Series Interpolation Algorithms in the Presence of Noise

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Niksefat, Roxana, Thesis advisor (ths): Burr, Wesley Dr, Degree granting institution (dgg): Trent University
    Abstract: <p>The spectral properties of time series data reveal underlying processes but require complete datasets, often unavailable due to missing values and irregular sampling.This thesis uses a computational simulations framework to evaluate the perfor- mance of the Hybrid Wiener Interpolator [3], a novel method designed to reconstruct nonstationary time series data, thus making said data… more

    The Localization and Functional Characterization of a DNAJC5-like Protein in Dictyostelium discoideum

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Singh, Jagjot, Thesis advisor (ths): Huber, Robert, Degree committee member (dgc): Bates, Holly, Degree committee member (dgc): Rafferty, Steven, Degree granting institution (dgg): Trent University
    Abstract: <p>DNAJC5, an HSP40 member, supports synaptic vesicle release and protein folding byactivating HSP70 ATPase activity. In humans, it localizes to presynaptic terminals and
    endomembrane compartments that are involved in protein trafficking. Mutations in DNAJC5
    cause CLN4 disease, a rare adult-onset Batten disease. Dictyostelium discoideum, a model for
    neurodegenerative research, encodes a… more

    Living with Lyme Disease Symptoms: Experiences and Adaptive Practices

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Sirohi, Naina, Thesis advisor (ths): Omar, Abeer, Thesis advisor (ths): Wahid, Rasha, Degree granting institution (dgg): Trent University
    Abstract: <p>Lyme disease (LD), caused by Borrelia burgdorferi, presents major diagnostic and treatment challenges due to its diverse symptoms and often ambiguous progression. Despite growing awareness, many patients face misdiagnosis, dismissal, and inadequate care—especially in North America, where brief treatment guidelines may fail to address persistent symptoms. This qualitative study used a… more

    Development of Models for Air Pollution-Related Public Health Assessment: Application of Long Short-Term Memory Neural Network for Short-term Exposure Effect

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Han, Huawei, Thesis advisor (ths): Burr, Wesley, Degree committee member (dgc): Parker, James, Degree committee member (dgc): Shin, Hwashin, Degree committee member (dgc): Chan-Reynolds, Michael, Degree granting institution (dgg): Trent University
    Abstract: <p>This thesis develops an Long Short-Term Memory (LSTM) neural network model to assess the relationship between ambient air pollutant exposure and public health risks, accommodating both linear and nonlinear associations with distributed lags.The research makes three key contributions. First, Maximal Information Coefficient (MIC) methods identify the most relevant air pollutants and their… more

    Psychological Adjustment and Psychological Flexibility Following Sport-related Concussion

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Pownall, Emma, Thesis advisor (ths): Brown, Liana E, Thesis advisor (ths): O'Hagan, Fergal, Degree committee member (dgc): Brenner, Ingrid, Degree granting institution (dgg): Trent University
    Abstract: <p>An athlete's psychological response to a sports-related concussion may influence thesuccess of recovery and return to play. This exploratory study explored how athletes
    psychologically respond to concussion, using Acceptance and Commitment Therapy to
    examine the role of psychological flexibility in recovery and return to play. Thirty
    athletes who experienced a concussion in the past… more

    Functional Role of 97R in Host Cell Modulation during Frog Virus 3 Infection

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bansal, Lakshika, Thesis advisor (ths): Brunetti, Craig R, Degree committee member (dgc): Tobin, Stephanie, Degree committee member (dgc): Yee, Janet, Degree granting institution (dgg): Trent University
    Abstract: <p>Frog virus 3 (FV3) belongs to the genus Ranavirus within the Iridoviridae family.Its 105,903 base genome encodes 98 open reading frames (ORFs), including ORF 97R, a
    putative apoptosis regulator sharing 31% structural similarity with the anti-apoptotic Bcl-
    2 family protein, myeloid cell leukemia 1 (Mcl-1). 97R contains a BH1 domain,
    implicated in apoptosis regulation, and a predicted C-… more

    Tamil Canadians Caregiving Experiences Caring for Older Adults with Dementia at Home

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Parama Thayanithi, Sumathi, Thesis advisor (ths): Omar, Abeer, Degree committee member (dgc): Wahid, Rasha, Degree committee member (dgc): Cable-Williams, Beryl, Degree granting institution (dgg): Trent University
    Abstract: <p>This study examines the experiences of Tamil Canadian caregivers providing home care for older adults with dementia, highlighting their unique challenges. Grounded in a social constructivist and phenomenological approach, the qualitative research explores the influence of social, cultural, and familial expectations on caregiving roles. Semi-structured interviews with ten Tamil Canadian… more

    Effects of a Topographical Gradient on Food Availability, Nest Site Selection, Nest Initiation, and Nest Success for Two Small, Low Arctic Breeding Bird Species

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bonnett, Sarah, Thesis advisor (ths): Nol, Erica, Thesis advisor (ths): Smith, Paul A, Degree committee member (dgc): Nol, Erica, Degree committee member (dgc): Smith, Paul A, Degree committee member (dgc): Brown, Glen, Degree granting institution (dgg): Trent University
    Abstract: <p>Climate change affects birds' reproductive ecology by altering breeding timing, distribution, and habitat suitability. Snowmelt patterns complicate these changes affecting habitat availability and suitability for birds and their arthropod prey. Snow varies as a function of both large-scale climate patterns and local-scale topography. I used elevational gradients as a proxy for local… more

    Guidance for Healthcare Professionals when Caring for People Who Use Drugs: A Perspective from Persons Who Use Drugs: A Scoping Review

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Brandsma, Julia, Thesis advisor (ths): Woodend, Kirsten, Thesis advisor (ths): Thibeault, Catherine, Degree committee member (dgc): King, Carolyn, Degree committee member (dgc): Churipuy, Donna, Degree committee member (dgc): Bedore, Christopher, Degree granting institution (dgg): Trent University
    Abstract: <p>Individuals who use drugs face stigma in healthcare, leading to poor health outcomes and limited treatment access. This scoping review aims to provide healthcare professionals with key evidence needed for delivering acceptable care from the perspective of those who use drugs. A Lived Experience Advisory Panel determined what contributions represented the perspective of people who use… more

    Rethinking Assessment: Students' Experiences, Learning Approaches, and Motivations in University Exams

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bodrug, Thomas Edward, Thesis advisor (ths): Keefer, Kateryna K, Degree committee member (dgc): Peters, Kevin R, Degree committee member (dgc): Celestini, Ann M, Degree granting institution (dgg): Trent University
    Abstract: <p>This thesis aimed to explore students' perspectives on university exams in two studies. Using a phenomenological approach, Study 1 recruited 10 senior undergraduate students to participate in semi-structured interviews. A thematic analysis revealed key themes related to exam purpose, effectiveness, fairness, and emotional responses. These insights informed the development of a… more

    Stand at Attention! Examining Postural Effects on Attention

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bolzon, Jenna M, Thesis advisor (ths): Chan-Reynolds, Michael G, Degree committee member (dgc): Brown, Liana E, Degree committee member (dgc): Treccani, Barbara, Degree granting institution (dgg): Trent University
    Abstract: <p>Office workers consistently report greater productivity in the workplace when standing compared to sitting (Chambers et al., 2019; MacEwan et al., 2015; Mantzari et al., 2018). In contrast, laboratory studies report inconsistent evidence that posture (sitting vs. standing) affects cognitive performance, usually operationalized as selective attention (Caron et al., 2020; 2022; Rosenbaum… more

    Statistical and Machine Learning Methods for Quantum Measurements with Single Photon Emitters

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Stone, Dylan, Thesis advisor (ths): Bradac, Carlo, Degree committee member (dgc): Atkinson, Bill, Degree committee member (dgc): Agarwal, Nisha, Degree committee member (dgc): Sadaf, Sharif, Degree granting institution (dgg): Trent University
    Abstract: <p>With wide applications ranging from quantum communication and metrology to biomedicine, single photon sources in solid-state hosts have become a major area of study. Here, we focus on three applications: nanothermometry, optically detected magnetic resonance (ODMR), and second order autocorrelation. We present novel statistical and machine learning (ML) approaches to extract information… more

    Exploring the Impact of Acute Stress on Previously Acquired Contextual Fear Memory

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Thiyagarajah, Javishaa, Thesis advisor (ths): Fournier, Neil, Degree committee member (dgc): Lehmann, Hugo, Degree committee member (dgc): Marks, Wendie, Degree granting institution (dgg): Trent University
    Abstract: <p>Stress can significantly affect neurobiological processes crucial for learning and memory. While repeated stress enhances fear memory, it impairs memory retrieval. In most studies, however, stress exposure typically preceded fear and extinction learning. Thus, the impact of previously acquired memories formed before exposure to stress is not well understood. The goal of this thesis is to… more

    Inorganic and Organic Carbon Dynamics of a South-Central Ontario Forest After the Application of Non-Industrial Wood Ash

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Foley, Kaylen, Thesis advisor (ths): Watmough, Shaun, Degree committee member (dgc): Power, Ian, Degree committee member (dgc): Thompson, Karen, Degree granting institution (dgg): Trent University
    Abstract: <p>Forests play a critical role in the global carbon cycle, acting as carbon sinks that remove and store an estimated 0.4 to 4.1 Pg of atmospheric carbon annually. However, historical acid deposition and timber harvesting have disrupted nutrient cycles, leading to nutrient-deficient soils that hinder tree growth, particularly for sugar maple (Acer saccharum), a keystone species in Ontario… more

    Differentiate and Conquer: Associations Between Self-Other Differentiation and Adaptive Capacity in Clinic-Referred and Typically Developing Adolescents

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): French, Alisa, Thesis advisor (ths): Im-Bolter, Nancie, Degree committee member (dgc): Bickle, Korri, Degree committee member (dgc): Eastabrook, Jennifer, Degree granting institution (dgg): Trent University
    Abstract: <p>This study investigates associations between self-other differentiation (the ability to distinguish and coordinate the self and other perspective during social problem-solving) and specific ego functions (reality testing, judgement, sense of reality, object relations, and synthetic-integrative function) from a cognitive perspective in two groups of adolescents aged 12 to 18 years. One… more

    An in vitro characterization of the novel binding properties of the Giardia TATA-binding protein

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Freitag, Kieran, Thesis advisor (ths): Yee, Janet, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Huber, Robert, Degree granting institution (dgg): Trent University
    Abstract: <p>The TATA-binding protein (TBP) is a key regulator of eukaryotic transcription initiation. The TBP homolog from Giardia intestinalis (gTBP) is highly divergent among all TBPs; notably lacking three of the four phenylalanine residues to unwind double- stranded DNA. I show that gTBP preferentially binds to single-stranded DNA (ssDNA) in two modes based on sequence and protein concentration… more

    Effect of mfsd8 deletion on the secretome and transcriptome of Dictyostelium discoideum

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Gray, Joshua, Thesis advisor (ths): Huber, Robert J, Degree committee member (dgc): Saville, Barry, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
    Abstract: <p>Mutations in the CLN7 (MFSD8) gene, causes CLN7 disease, a subtype of neuronal ceroid lipofuscinosis. MFSD8 is a lysosomal transmembrane protein that transports chloride across membranes. Experimentation regarding Dictyostelium discoideum revealed that mfsd8 deficiency altered lysosomal enzyme activity. During starvation, the aggregation of mfsd8¬¬- cells was delayed, and cells formed… more

    Effect of Polarization on the Band Structure at a Charged Domain Wall in Ferroelectric Materials

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Nasir, Maryam, Thesis advisor (ths): Atkinson, William WA, Degree committee member (dgc): Bradac, Carlo CB, Degree committee member (dgc): de Haan, Hendrick, Degree committee member (dgc): Ramachandran, Ganesh GR, Degree granting institution (dgg): Trent University
    Abstract: <p> The interplay between electron charge, spin, and ferroelectric polarization is under-explored for conducting ferroelectric domain walls (DWs). DWs are interfaces that separate regions
    (domains) within a material that have different orientations of spontaneous polarization.
    We investigated the electronic band structure of t2g electrons, confined to 90° charged do
    main walls (CDWs) in… more

    Exploring End-User Accessible Microsatellite and Microhaplotype Nanopore Sequencing with the Oxford Nanopore's MinION Device

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Clarke, Ella, Thesis advisor (ths): Wilson, Paul, Thesis advisor (ths): Manseau, Micheline, Degree committee member (dgc): Smith, Derek, Degree granting institution (dgg): Trent University
    Abstract: <p>Microsatellites and microhaplotypes are genetic markers that, through DNA amplicon sequencing, generate genotypes to distinguish between individuals from wildlife populations. Here, these markers were sequenced in caribou (Rangifer tarandus) specimens using Oxford Nanopore's MinION DNA sequencer for the first time. Microsatellite loci previously sequenced with an Illumina MiSeq were… more