Trent University Graduate Thesis Collection

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    The Taming of the Shrew('s Genome): An Omics Approach to Studying the World's Smallest Mammals

    Year: 2026, 2026
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Cossette, Marie-Laurence, Thesis advisor (ths): Shafer, Aaron B A, Thesis advisor (ths): Stewart, Donald T, Degree committee member (dgc): Freeland, Joanna, Degree granting institution (dgg): Trent University
    Abstract: <p>The diversification of mammals has been shaped by climatic fluctuations and geological changes over millions of years. Among them, shrews (Soricidae) stand out as one of the most diverse mammalian lineages. Shrews are found on most continents and have evolved remarkable adaptations at the species and population levels. Although evolutionary studies of shrews have been limited by a lack… more

    Understanding the Relationships Between Land Disturbance, Mercury and Fishing Practices in the Moose Cree Territory: A Foundation for Risk Assessment

    Year: 2026, 2026
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Miceli, Emily Jane, Thesis advisor (ths): Buell, Mary-Claire, Thesis advisor (ths): Hintelmann, Holger, Degree committee member (dgc): Furgal, Chris, Degree granting institution (dgg): Trent University
    Abstract: <p>The ᐃᓕᓕᐗᔅᑭᔾ | Ililiwaskiy (Moose Cree First Nation Territory) in Ontario's James Bay region has long faced industrial impacts on its ecosystems. Community concerns about mercury in culturally important fish prompted an interdisciplinary study bringing together chemical analysis and community knowledge. Researchers partnered with Moose Cree members through workshops, training, and… more

    Belowground plant strategies for improved carbon sequestration in diversified agroecosystems

    Year: 2026, 2026
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Cassidy, Aleisha, Thesis advisor (ths): Borden, Kira, Degree committee member (dgc): Watkinson, Autumn, Degree committee member (dgc): Thompson, Karen, Degree granting institution (dgg): Trent University
    Abstract: <p>Diversified agroecosystems supporting greater genetic, structural, and functional diversity improve soil health and ecosystem function. However, there is limited understanding of how multiple forms of diversification, such as mixing cover crop species and adding arbuscular mycorrhizal fungi (AMF), alter belowground carbon supply to soil. In a controlled environment experiment using… more

    Uncovering mechanisms of cadmium tolerance in a Euglena mutabilis fungal-algal-bacterial (FAB) consortium

    Year: 2026, 2026
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Kaszecki, Emma, Thesis advisor (ths): Saville, Barry J, Thesis advisor (ths): Emery, R. J. Neil, Degree committee member (dgc): Morrsion, Erin N, Degree committee member (dgc): Thompson, Karen A, Degree granting institution (dgg): Trent University
    Abstract: <p>Acid mine drainage (AMD) and metal-contaminated tailings represent some of the most inhospitable aquatic environments on Earth, characterized by low pH, elevated metal concentrations, and chronic carbon limitation. Yet these systems support microbial consortia with remarkable resilience. Among the most conspicuous inhabitants is Euglena mutabilis, an acidophilic protist traditionally… more

    Using the Social Amoeba Dictyostelium discoideum as a Model to Study CLN5 Disease

    Year: 2026, 2026
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Kim, William David, Thesis advisor (ths): Huber, Robert J, Degree committee member (dgc): Donaldson, Michael, Degree committee member (dgc): Shafer, Aaron, Degree committee member (dgc): Saville, Barry, Degree granting institution (dgg): Trent University
    Abstract: <p>The neuronal ceroid lipofuscinoses (NCLs), collectively referred to as Batten disease, are a group of neurodegenerative diseases that affect all ages, primarily children. Batten disease is caused by mutations in 1 of the 13 ceroid lipofuscinosis neuronal (CLN) genes (CLN1-CLN8, CLN10-CLN14), each of which causes an NCL subtype when mutated. One of the NCL subtypes, CLN5 disease, is… more

    Hybridisation and Speciation in the Genus Typha

    Year: 2026, 2026
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Lopez Aleman, Jose Alberto, Thesis advisor (ths): Dorken, Marcel E, Thesis advisor (ths): Freeland, Joanna R, Degree committee member (dgc): Shafer, Aaron AB, Degree committee member (dgc): DiLeo, Michelle F, Degree granting institution (dgg): Trent University
    Abstract: <p>Hybridisation is an important evolutionary mechanism with diverse outcomes, including the formation of new lineages, the exchange of alleles between species, or their extinction through genetic swamping. In some cases, hybrids exhibit higher fitness than their parental species, which can lead to hybrid invasions that threaten ecosystems. In North America, hybridisation between the native… more

    Cytokinin-Mediated Amyloid Inhibition and Its Role in Alleviating Oxidative Stress: An Analytical Study on Antioxidant Defense and Protein Oxidation

    Year: 2026, 2026
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Seneviratne, Dev, Thesis advisor (ths): Martic, Sanela, Thesis advisor (ths): Emery, Neil, Degree committee member (dgc): Oleschuk, Richard, Degree committee member (dgc): Moorthy, Arun, Degree committee member (dgc): Burr, Wesley, Degree granting institution (dgg): Trent University
    Abstract: <p>Amyloid fibrils are fibrous protein aggregates that arise from misfolding and self-assembly processes, collectively referred to as amyloidosis. These aggregates are strongly associated with incurable neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease, and Amyotrophic Lateral Sclerosis (ALS). Elevated levels of Reactive Oxygen Species (ROS) and… more

    Chromophoric dissolved organic matter in the Athabasca Oil Sands Region, Alberta, Canada

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Blanchard, Dane Alexander, Thesis advisor (ths): Aherne, Julian, Thesis advisor (ths): Gordon, Mark, Degree committee member (dgc): Aherne, Julian, Degree committee member (dgc): Gordon, Mark, Degree committee member (dgc): Dang, Huy, Degree committee member (dgc): Koprivnjak, Jean-François, Degree committee member (dgc): Mangal, Vaughn, Degree granting institution (dgg): Trent University
    Abstract: <p>Chromophoric dissolved organic matter (CDOM), a chemically diverse family of organic compounds defined by their ability to absorb ultraviolet and visible light, is a critical constituent of numerous environmental systems, including freshwater lakes. Industrial operations in the Athabasca Oil Sands Region (AOSR, Alberta, Canada) are major sources of acidic inorganic gases and organic… more

    The biogeochemical effects of non-industrial wood ash application on ecosystem regeneration in central Ontario

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bewsh, Victor Michael, Thesis advisor (ths): Watmough, Shaun A, Degree committee member (dgc): Sager, Eric PS, Degree committee member (dgc): Watkinson, Autumn D, Degree granting institution (dgg): Trent University
    Abstract: <p>Decades of sulphur and nitrogen deposition acidified forest ecosystems across northeastern North America causing declines in pH and exchangeable base cation concentrations, negatively affecting biota. To assist natural recovery, researchers are investigating using alkaline soil amendments such as wood ash. However, much remains unknown about its use. This thesis evaluated the effects of… more

    Sexual Selection, Sex Allocation and Stochasticity: A Study of Mating Patterns in Sagittaria latifolia

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Kwok, Allison, Thesis advisor (ths): Dorken, Marcel E, Degree committee member (dgc): Freeland, Joanna R, Degree committee member (dgc): Nol, Erica, Degree granting institution (dgg): Trent University
    Abstract: <p>Diversity of flowers in flowering plants is understood to facilitate mating success, and yet understanding the relationships between plant sexual diversity and mating patterns remains a challenge. In this thesis, I used Sagittaria latifolia, an aquatic plant with unique sexual systems, to investigate relationships between plant sexual diversity, mating patterns, and reproductive success… more

    Dissolved organic matter composition as a driver of greenhouse gas emissions in lakes

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Lau, Vincent, Thesis advisor (ths): Tanentzap, Andrew, Degree committee member (dgc): Emilson, Erik, Degree committee member (dgc): Stock, Naomi, Degree committee member (dgc): Moorthy, Arun, Degree committee member (dgc): Braga, Lucas, Degree granting institution (dgg): Trent University
    Abstract: <p>Climate-driven permafrost thaw releases microorganisms and dissolved organic matter (DOM) into northern lakes, where their interactions with microbial communities and seasonal processes shape greenhouse gas emissions. In a factorial experiment mixing DOM and microbes from thermokarst ponds and lakes, we found that both DOM and microbial identity strongly influenced degradation. Lake… more

    Method Development of Compound Specific Isotope Ratio Measurement of Methylmercury in Sediment by Multicollector - ICP - MS

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Willsie, Adelheid, Thesis advisor (ths): Hintelmann, Holger, Degree committee member (dgc): Canario, João, Degree committee member (dgc): Dang, Huy, Degree granting institution (dgg): Trent University
    Abstract: <p>This work presents a new online method using gas chromatography coupled to the multicollector-inductively coupled plasma-mass spectrometer for methylmercury (MMHg) isotope ratio measurement. An extraction method using distillation was developed that effectively extracted MMHg from up to 5 grams of sediment, imparting no isotope fractionation on MMHg during extraction. Isotope ratios from… more

    Rare earth and trace element geochemistry in Ontario agricultural soils

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Wetzl, Ruby J., Thesis advisor (ths): Thompson, Karen A., Thesis advisor (ths): Dang, Huy, Degree committee member (dgc): Watmough, Shaun, Degree granting institution (dgg): Trent University
    Abstract: <p>Agriculture may result in soil disturbances, including contamination by rare earth elements (REE) and trace elements (TEs) from agricultural inputs (e.g. fertilizers, pesticides). Regulations concerning agricultural inputs currently do not consider TE background concentrations, concurrent use of inputs, and emerging contaminants. Therefore, they may not sufficiently protect against TE… more

    Naturalizing Naturalization: Accounting for Naturalization in Ecology and Ecological Management

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Weissflog, Nicholas, Thesis advisor (ths): Sager, Eric PS, Thesis advisor (ths): Whillans, Thomas H, Degree committee member (dgc): Beresford, David V, Degree granting institution (dgg): Trent University
    Abstract: <p>This thesis presents a case of the aquatic plant species Fanwort (Cabomba caroliniana) significantly naturalizing in Kasshabog Lake in bays where it had been invasive. This significant naturalization presents major implications for invasive species management and invasion biology because the naturalization of invasive species is a phenomenon that has been largely omitted from study… more

    Behavioural Responses of Nocturnally Stranded Seabirds Toward Artificial Light, and Implications for Rescue Programs

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Brown, Taylor Marie, Thesis advisor (ths): Burness, Gary, Degree committee member (dgc): Davy, Christina, Degree committee member (dgc): Mastromonaco, Gabriela, Degree committee member (dgc): Wilhelm, Sabina, Degree granting institution (dgg): Trent University
    Abstract: <p>Globally, fledglings of more than 50 seabird species are vulnerable to stranding in human settlements near their colonies as they leave their nests for the first time. This phenomenon has been attributed to attraction toward and disorientation by artificial light at night (ALAN). Grassroots rescue programs find more birds in illuminated locations than in dark ones, but it is unclear to… more

    Factors Affecting Nest Survival and Nest Site Selection for the Lesser Yellowlegs (Tringa flavipes)

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Brown, Courtland Weston, Thesis advisor (ths): Nol, Erica, Thesis advisor (ths): Christie, Katie, Degree committee member (dgc): Smith, Paul A., Degree granting institution (dgg): Trent University
    Abstract: <p>The Lesser Yellowlegs (Tringa flavipes) is a steeply declining shorebird that breeds across boreal North America. I studied nest survival in Anchorage, Alaska, USA and Churchill, Manitoba, Canada and nest site selection factors in Churchill. Nests were monitored at each site and daily nest survival rates (DSR) were calculated based on a maximum likelihood approach. Overall nest survival… more

    Microplastic Contamination in the Canadian Arctic, Iqaluit, Nunavut

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Evans, Kelly, Thesis advisor (ths): Aherne, Julian, Degree committee member (dgc): Jantunen, Liisa, Degree committee member (dgc): McKenna-Neuman, Cheryl, Degree granting institution (dgg): Trent University
    Abstract: <p>Microplastics are intricate plastic particles (&lt;5 mm in length) with complex chemical mixtures that are pervasive globally. Nonetheless, our understanding of microplastic contamination in the Canadian Arctic is limited. Therefore, this thesis aimed to investigate the concentration and characteristics of microplastics in and surrounding the community of Iqaluit, Nunavut. Our… more

    Electroactive Supramolecular Systems for Informed Electrochemical Sensor Development

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Quintero Arias, Carlos, Thesis advisor (ths): Martic, Sanela, Degree committee member (dgc): Keske, Eric, Degree committee member (dgc): Thompson, Karen, Degree granting institution (dgg): Trent University
    Abstract: <p>In an effort to improve upon existing analytical methods, electrochemical sensors offer portable, cost-effective alternatives to traditional lab-based techniques. Recent advances in supramolecular chemistry offer a unique alternative to achieve high selectivity while also benefitting from facile scaling for mass production. Thus, by incorporating host-guest chemistry with electrochemical… more

    DNA methylation and phenotypic variation in three North American large mammals

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Czajka, Natalie, Thesis advisor (ths): Shafer, Aaron B.A., Thesis advisor (ths): Northrup, Joseph M., Degree granting institution (dgg): Trent University
    Abstract: <p>DNA methylation (DNAm) is a useful indicator of phenotypic expression and diversity, and can potentially inform adaptations to environmental changes. This thesis uses epigenetic techniques to investigate the mechanisms underlying phenotypic variation in white-tailed deer, black bear, and mountain goat, with a particular focus on age and body size. In the second chapter, we aimed to… more

    The phytochemical therapeutic potential of Doliocarpus dentatus Red and White Ecotypes: Metabolomics, phytohormone profiles and Antioxidant Properties

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Smith, Ewart Anthony, Thesis advisor (ths): Emery, Neil NE, Thesis advisor (ths): Narine, Suresh SN, Degree committee member (dgc): Martic, Sanela SM, Degree committee member (dgc): Kisiala, Anna AK, Degree granting institution (dgg): Trent University
    Abstract: <p>The study examines the phytochemical and phytohormone profiles of two ecotypes of Doliocarpus dentatus (Capadulla) from Guyana with an emphasis on their potential therapeutic applications, particularly in the context of erectile dysfunction. The research concentrates on the red and white ecotypes, which are visibly differentiated by the colouration of their inner and outer bark; moreover… more

    The Localization and Functional Characterization of a DNAJC5-like Protein in Dictyostelium discoideum

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Singh, Jagjot, Thesis advisor (ths): Huber, Robert, Degree committee member (dgc): Bates, Holly, Degree committee member (dgc): Rafferty, Steven, Degree granting institution (dgg): Trent University
    Abstract: <p>DNAJC5, an HSP40 member, supports synaptic vesicle release and protein folding byactivating HSP70 ATPase activity. In humans, it localizes to presynaptic terminals and
    endomembrane compartments that are involved in protein trafficking. Mutations in DNAJC5
    cause CLN4 disease, a rare adult-onset Batten disease. Dictyostelium discoideum, a model for
    neurodegenerative research, encodes a… more

    Genetic, Genomic and Diet Diversity: Insight into the Persistence and Vulnerability of Muskoxen (Ovibos moschatus)

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Prewer, Erin, Thesis advisor (ths): Kyle, Christopher J, Degree committee member (dgc): Donaldson, Michael, Degree committee member (dgc): Shafer, Aaron, Degree committee member (dgc): Saville, Barry, Degree granting institution (dgg): Trent University
    Abstract: <p>Molecular and genomic tools provide a deeper understanding of the ecology and evolution of species and their capacity to adapt to changing selective pressures, where diversity is presumedly linked to higher fitness and evolutionary potential. Molecular tools can also illustrate how historical processes affect contemporary genetic variation to predict how current population trends may… more

    Host Population Immunogenetics in a Changing World: Signatures of Selection in the Context of Endemic and Invasive Diseases in Wildlife

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Baecklund, Tristan Mackenzie, Thesis advisor (ths): Kyle, Christopher J, Degree committee member (dgc): Donaldson, Michael, Degree committee member (dgc): Shafer, Aaron, Degree committee member (dgc): Brown, Glen, Degree granting institution (dgg): Trent University
    Abstract: <p>Heterogeneous environments impose discordant selective pressures on natural populations, where disparate biotic/abiotic factors and variable population connectivity, yield mosaic patterns of genetic variation on the landscape. The ability to maintain or change genetic mosaics of populations becomes key to persistence, as species increasingly need to adapt to rapidly changing… more

    Axes of diversity and their implications in the unisexual Ambystoma complex

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bare, Evan, Thesis advisor (ths): Murray, Dennis, Thesis advisor (ths): Hossie, Thomas, Degree committee member (dgc): Bogart, Jim, Degree committee member (dgc): Wilson, Chris, Degree granting institution (dgg): Trent University
    Abstract: <p>Measuring biodiversity has become increasingly complex as biologists and ecologists have gradually learned more about how biotic systems are structured and interact. Given the wide range of tools, techniques and approaches now in use to quantify biological diversity, it is useful to consider different "dimensions of diversity" to classify these measurements and provide context… more

    Functional Role of 97R in Host Cell Modulation during Frog Virus 3 Infection

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bansal, Lakshika, Thesis advisor (ths): Brunetti, Craig R, Degree committee member (dgc): Tobin, Stephanie, Degree committee member (dgc): Yee, Janet, Degree granting institution (dgg): Trent University
    Abstract: <p>Frog virus 3 (FV3) belongs to the genus Ranavirus within the Iridoviridae family.Its 105,903 base genome encodes 98 open reading frames (ORFs), including ORF 97R, a
    putative apoptosis regulator sharing 31% structural similarity with the anti-apoptotic Bcl-
    2 family protein, myeloid cell leukemia 1 (Mcl-1). 97R contains a BH1 domain,
    implicated in apoptosis regulation, and a predicted C-… more

    Cytokinin-Producing Methylobacterium as Biological Control Agents of Phytopathogens

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Palberg, Daniel Michael, Thesis advisor (ths): Emery, R. J. Neil, Degree committee member (dgc): Stock, Naomi L, Degree committee member (dgc): Morrison, Erin, Degree granting institution (dgg): Trent University
    Abstract: <p>Methylobacterium spp., a dominant and functionally conserved group of plant-associated bacteria, have long been recognized for their roles in promoting host growth, stress tolerance, and phytohormone modulation. This body of work collectively repositions Methylobacterium not only as a plant growth-promoting genus but also as a promising agent of microbiome-mediated crop protection.… more

    Environmental contamination associated with artisanal gold mining in Guyana

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Osborne, Chetwynd Carlos, Thesis advisor (ths): Watmough, Shaun A., Degree committee member (dgc): Eimers, Catherine, Degree committee member (dgc): Hintelmann, Holger, Degree granting institution (dgg): Trent University
    Abstract: <p>A meta-analysis revealed that while there is often a greater degree of contamination of soils and sediments with metals, contamination by mercury (Hg) is a large concern owing to its toxicity at low concentrations. The case study in Guyana characterized Hg and concentrations of other metals (As, Cd, Co, Cu, Mn, Ni, Pb, and Zn) in soil and sediment within gold mined areas. Metal… more

    Effects of a Topographical Gradient on Food Availability, Nest Site Selection, Nest Initiation, and Nest Success for Two Small, Low Arctic Breeding Bird Species

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Bonnett, Sarah, Thesis advisor (ths): Nol, Erica, Thesis advisor (ths): Smith, Paul A, Degree committee member (dgc): Nol, Erica, Degree committee member (dgc): Smith, Paul A, Degree committee member (dgc): Brown, Glen, Degree granting institution (dgg): Trent University
    Abstract: <p>Climate change affects birds' reproductive ecology by altering breeding timing, distribution, and habitat suitability. Snowmelt patterns complicate these changes affecting habitat availability and suitability for birds and their arthropod prey. Snow varies as a function of both large-scale climate patterns and local-scale topography. I used elevational gradients as a proxy for local… more

    Environmental Remediation Applications of Chemically Activated Tropical Hardwood Waste

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): France, Hamant Edward, Thesis advisor (ths): Vreugdenhil, Andrew J, Degree committee member (dgc): Martic, Sanela, Degree committee member (dgc): Narine, Suresh, Degree granting institution (dgg): Trent University
    Abstract: <p>Innovative strategies to manage copious waste streams by upcycling feedstocks to valorized products which are then used in environmental remediation applications is an attractive circular economy model. This thesis explores this approach using waste wood generated from the milling of Chlorocardium rodiei (greenheart), a tropical hardwood species abundant in Guyana. We evaluate the… more

    Inorganic and Organic Carbon Dynamics of a South-Central Ontario Forest After the Application of Non-Industrial Wood Ash

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Foley, Kaylen, Thesis advisor (ths): Watmough, Shaun, Degree committee member (dgc): Power, Ian, Degree committee member (dgc): Thompson, Karen, Degree granting institution (dgg): Trent University
    Abstract: <p>Forests play a critical role in the global carbon cycle, acting as carbon sinks that remove and store an estimated 0.4 to 4.1 Pg of atmospheric carbon annually. However, historical acid deposition and timber harvesting have disrupted nutrient cycles, leading to nutrient-deficient soils that hinder tree growth, particularly for sugar maple (Acer saccharum), a keystone species in Ontario… more

    An in vitro characterization of the novel binding properties of the Giardia TATA-binding protein

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Freitag, Kieran, Thesis advisor (ths): Yee, Janet, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Huber, Robert, Degree granting institution (dgg): Trent University
    Abstract: <p>The TATA-binding protein (TBP) is a key regulator of eukaryotic transcription initiation. The TBP homolog from Giardia intestinalis (gTBP) is highly divergent among all TBPs; notably lacking three of the four phenylalanine residues to unwind double- stranded DNA. I show that gTBP preferentially binds to single-stranded DNA (ssDNA) in two modes based on sequence and protein concentration… more

    Effect of mfsd8 deletion on the secretome and transcriptome of Dictyostelium discoideum

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Gray, Joshua, Thesis advisor (ths): Huber, Robert J, Degree committee member (dgc): Saville, Barry, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
    Abstract: <p>Mutations in the CLN7 (MFSD8) gene, causes CLN7 disease, a subtype of neuronal ceroid lipofuscinosis. MFSD8 is a lysosomal transmembrane protein that transports chloride across membranes. Experimentation regarding Dictyostelium discoideum revealed that mfsd8 deficiency altered lysosomal enzyme activity. During starvation, the aggregation of mfsd8¬¬- cells was delayed, and cells formed… more

    Exploring End-User Accessible Microsatellite and Microhaplotype Nanopore Sequencing with the Oxford Nanopore's MinION Device

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Clarke, Ella, Thesis advisor (ths): Wilson, Paul, Thesis advisor (ths): Manseau, Micheline, Degree committee member (dgc): Smith, Derek, Degree granting institution (dgg): Trent University
    Abstract: <p>Microsatellites and microhaplotypes are genetic markers that, through DNA amplicon sequencing, generate genotypes to distinguish between individuals from wildlife populations. Here, these markers were sequenced in caribou (Rangifer tarandus) specimens using Oxford Nanopore's MinION DNA sequencer for the first time. Microsatellite loci previously sequenced with an Illumina MiSeq were… more

    Environmental and Genetic Factors Influencing Trait Variation in White-Tailed Deer

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Cars, Brooklyn Shirley, Thesis advisor (ths): Shafer, Aaron BA, Degree granting institution (dgg): Trent University
    Abstract: <p>Trait variation in wild populations is shaped by the interaction of genetics and the environment. Given these interactions, this thesis explored trait variation in white-tailed deer from two angles: one focused on broad-scale environmental factors, the other on fine-scale genetic mechanisms. The first chapter investigated how climate and habitat variation influence antler size,… more

    Genomic Perspectives on the Evolutionary History of North American Cervidae: Ancient DNA, Demographic Collapse and Hybridisation

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Kessler, Camille Pauline, Thesis advisor (ths): Shafer, Aaron B. A., Degree committee member (dgc): Foote, Andrew D., Degree committee member (dgc): Spzak, Paul, Degree granting institution (dgg): Trent University
    Abstract: <p>Since the mid-Pleistocene, evolutionary histories of North American species were shaped by extreme climatic oscillations involving major range and habitat shifts at a rapid pace. The peopling of the continent and the subsequent human colonisation waves created further pressures affecting North American faunal and plant populations. Cervidae (deer family) are a diverse group which arrived… more

    The biogeochemical fate of rare earth elements in aquatic ecosystems

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Kernaghan, Ashlyn, Thesis advisor (ths): Dang, Huy D, Degree committee member (dgc): Fortin, Claude, Degree committee member (dgc): Watmough, Shaun, Degree granting institution (dgg): Trent University
    Abstract: <p>Rare earth elements (REEs) are in high demand globally for the green transition and high technologies. The growing demand leads to their release into aquatic ecosystems from various point and non-point sources, which creates urgency to investigate their fate and enrichment. This thesis further investigates the biogeochemical fate and REE uptake mechanisms throughout aquatic ecosystems.… more

    Investigation of the Oxidative Activity of Giardia Flavohemoglobins

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Decorso, Isabelle, Thesis advisor (ths): Rafferty, Steven, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Martic, Sanela, Degree granting institution (dgg): Trent University
    Abstract: <p>Flavohemoglobins are enzymes primarily implicated in nitrosative stress due to their high nitric oxide (NO) dioxygenase activity and transcriptional upregulation in response to NO. Giardia intestinalis assemblages A, B, and E possess flavohemoglobins (gFlHb) that may function beyond their NO dioxygenase activity, potentially contributing to oxidative stress regulation, as transcriptional… more

    Impacts of wildfire on dissolved organic matter in boreal headwater streams

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Matula, Erin Rae, Thesis advisor (ths): Tanentzap, Andrew, Thesis advisor (ths): Emilson, Erik, Degree committee member (dgc): Watmough, Shaun, Degree granting institution (dgg): Trent University
    Abstract: <p>Increasing wildfire frequency, driven by climate change, can change the concentration andcomposition of dissolved organic matter (DOM) exported from land into receiving waters by
    removing terrestrial vegetation, changing soil hydrology, and interrupting microbial degradation.
    In this thesis, I tested how wildfire impacts the molecular composition and reactivity of DOM. I
    compared DOM… more

    Survival and roost selection of eastern wild turkeys in their northern range

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Martin, Kayla, Thesis advisor (ths): Bowman, Jeff, Thesis advisor (ths): Burness, Gary, Degree committee member (dgc): Feldman, Richard, Degree granting institution (dgg): Trent University
    Abstract: <p>Understanding habitat needs of a species is critical, especially for species reintroduced to an area or expanding their range. I evaluated roost tree selection and survival probability of GPS-tagged eastern wild turkeys (Meleagris gallopavo silvestris) from 2017–2020 and 2022 in Peterborough County, Ontario, Canada. Fine-scale roost tree selection was associated with larger trees, with… more

    The first confirmation that Insects synthesize Cytokinins: Cytokinin metabolite and gene expression profiling following functional manipulations of tRNA IPT genes in Drosophila melanogaster

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Andreas, Peter Frank, Thesis advisor (ths): Emery, R.J. N, Degree committee member (dgc): Beresford, David V, Degree committee member (dgc): Kisiala, Anna B, Degree committee member (dgc): Morrison, Erin N, Degree granting institution (dgg): Trent University
    Abstract: <p>Using Drosophila deficiency (Df) and Over Expression (OE) (GAL4/UAS&gt;dCas9-VPR; sgRNA) gene systems, it was demonstrated that Dmel_CG31381 and Dmel_CG11089 are functional tRNA isopentenyltransferase (EC 2.5.1.8) genes (tRNA IPT1 and IPT2) critical to the first committed step in insect cytokinin biosynthesis. IPT Df mutants showed significant decreases in total CK levels and IPT1/… more

    A Systematic Review of the Prognostic Value of Cardiopulmonary Exercise Testing in Patients with Diverse Heart Failure Etiolgies

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Lowes, William Holden Hubert, Thesis advisor (ths): Brenner, Ingrid, Degree committee member (dgc): Woodend, Kirsten, Degree committee member (dgc): West, Sarah, Degree committee member (dgc): Moayedi, Yas, Degree granting institution (dgg): Trent University
    Abstract: <p>Heart failure (HF) is a condition with several possible etiologies that influence patient symptomatology, including response to exercise. The purpose of this review was to assess how cardiopulmonary exercise testing (CPET) parameters used for risk stratification differ and are associated with mortality and adverse cardiac events in patients with different HF etiologies. We completed a… more

    Phenology and Movement Ecology of Mid-Atlantic Breeding Shorebirds

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): MacLaurin, Trevor, Thesis advisor (ths): Nol, Erica, Degree committee member (dgc): Smith, Paul A., Degree committee member (dgc): Senner, Nathan R., Degree granting institution (dgg): Trent University
    Abstract: <p>Migration, space use, and phenology play key roles in shaping avian populations and are therefore critical for conservation. My thesis examines the migration strategies and non-breeding spatial requirements of Virginia's beach-nesting American Oystercatchers (Haematopus palliatus), as well as the nesting phenology of mid-Atlantic American Oystercatchers and Piping Plovers (… more

    Transcriptome Changes and the Role of RNA Helicases in Ustilago maydis During Teliospore Dormancy and Germination

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Seto, Amanda, Thesis advisor (ths): Saville, Barry J, Degree committee member (dgc): Brunetti, Craig, Degree committee member (dgc): Yee, Janet, Degree granting institution (dgg): Trent University
    Abstract: <p>Crop losses due to pathogens, pests, and weeds account for 20–40% of global production, with fungal pathogens responsible for the most significant yield reductions and economic impact. The diseases caused by fungi spread through dormant spores, which protect its genetic material under adverse conditions. Dormancy is maintained until favorable germination conditions are met. Despite their… more

    Advancing the methodology used in fish telemetry tracking

    Year: 2025, 2025
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Shorgan, Mitchell, Thesis advisor (ths): Raby, Graham D, Thesis advisor (ths): Fisk, Aaron T, Degree committee member (dgc): de Kerckhove, Dak, Degree granting institution (dgg): Trent University
    Abstract: <p>This thesis aimed to address potential sources of bias in electronic fish tagging studies in order to advance the methods used by future studies. I first provided a review and meta-analysis of intracoelomic tagging effects in fishes, summarizing the existing literature and assessing the extent to which previously identified research gaps have been filled. I also included the first large-… more

    The effects of forest disturbance on dissolved organic carbon in the Algoma region, central Ontario

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Watkins, Matthew, Thesis advisor (ths): Buttle, Jim, Thesis advisor (ths): Leach, Jason, Degree committee member (dgc): Emilson, Erik, Degree granting institution (dgg): Trent University
    Abstract: <p>Many communities in Canada rely on water sourced from boreal forest headwaters for their drinking water. The Boreal Shield Ecozone is highly susceptible to climate change which threatens to exacerbate the effects of natural and human-driven disturbances such as wildfire, insect infestation and harvesting on water quality. Therefore, examining source water quality in headwater catchments… more
    Full Text: The effects of forest disturbance on dissolved organic carbon in the Algoma region, central Ontario A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of …

    Within-Generation and Transgenerational Thermal Plasticity in Cold-Adapted Salmonids of the Genus Salvelinus

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Penney, Chantelle, Thesis advisor (ths): Wilson, Chris C, Thesis advisor (ths): Burness, Gary, Degree committee member (dgc): Scott, Graham, Degree committee member (dgc): Craig, Paul, Degree committee member (dgc): Freeland, Joanna, Degree granting institution (dgg): Trent University
    Abstract: <p>Climate change is a major conservation concern, especially for many cold-adapted species. The rate of warming due to climate change will likely outpace adaptive responses, and many populations will likely need to rely on phenotypic plasticity to cope with environmental warming. It is currently unclear whether plasticity in physiological responses to warming will be sufficient to offset… more
    Full Text: WITHIN-GENERATION AND TRANSGENERATIONAL THERMAL PLASTICITY IN COLD-ADAPTED SALMONIDS OF THE GENUS SALVELINUS A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfilment of the Requirements for the Degree of Doctor of Philosophy in the …

    The ecological, evolutionary, and behavioural context of ultrasonic vocalizations in flying squirrels

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Newar, Sasha Lynn, Thesis advisor (ths): Bowman, Jeff, Degree committee member (dgc): Davy, Christina M, Degree committee member (dgc): Burness, Gary, Degree granting institution (dgg): Trent University
    Abstract: <p>Acoustic communication is vital for mediating interactions between individuals and their environment. From echolocating bats to isolated rodent pups, ultrasonic vocalizations are a useful mechanism for producing localized and cryptic acoustic signals. Flying squirrels have been demonstrated to produce almost exclusively ultrasonic calls which is rare in both squirrels and mammals, though… more
    Full Text: The ecological, evolutionary, and behavioural context of ultrasonic vocalizations in flying squirrels A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfilment of the Requirements for the Degree of Doctor of Philosophy in the Faculty …

    Assessing Mercury and Methylmercury levels in the Wabigoon River with special attention on mercury methylation

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Paiva Bento, Beatriz, Thesis advisor (ths): Hintelmann, Holger, Degree granting institution (dgg): Trent University
    Abstract: <p>The Wabigoon River is known for an historic mercury (Hg) pollution source, caused by a chlor-alkali facility operating in the 1960s. As legacy Hg contamination continues to cause serious adverse health effects to the local communities living in the Wabigoon River region, it is imperative to undertake additional research to understand the deposition and transport of historical mercury in… more
    Full Text: Assessing Mercury and Methylmercury levels in the Wabigoon River with special aten�on on mercury methyla�on A Thesis Submited to the Commitee on Graduate Studies in Par�al Fulfilment of the Requirements for the Degree of Doctor of Philosophy in the Faculty …

    Conservation Genomics of the Lake Superior Caribou

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Solmundson, Kirsten, Thesis advisor (ths): Wilson, Paul, Thesis advisor (ths): Bowman, Jeff, Degree committee member (dgc): Patterson, Brent, Degree committee member (dgc): Manseau, Micheline, Degree granting institution (dgg): Trent University
    Abstract: <p>Globally, wildlife populations are experiencing increasing rates of range loss, population decline, and extinction. Caribou (Rangifer tarandus) have experienced dramatic declines in both range and population size across Canada over the past century. Boreal caribou (R. t. caribou), one of twelve Designatable Units, have lost approximately half of their historic range in the last 150 years… more
    Full Text: CONSERVATION GENOMICS OF THE LAKE SUPERIOR CARIBOU A dissertation submitted to the Committee on Graduate Studies in partial fulfilment of the requirements for the degree of Doctor of Philosophy in the Faculty of Arts and Science TRENT UNIVERSITY …

    Investigation of Dynamics of Particulate Transport under Varying Climate Conditions

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Schweighofer, Christopher John, Thesis advisor (ths): McKenna Neuman, Cheryl, Degree committee member (dgc): Power, Ian, Degree committee member (dgc): Aherne, Julian, Degree granting institution (dgg): Trent University
    Abstract: <p>A key knowledge gap in aeolian transport research concerns the adjustment of saltation processes to the extreme conditions found within high-latitude regions. A series of wind tunnel experiments were carried out under full climate control and over a wide range in humidity. Particle entrainment and transport within shearing flows of varied wind speed were monitored over beds of varied… more
    Full Text: i INVESTIGATION OF DYNAMICS OF PARTICULATE TRANSPORT UNDER VARYING CLIMATE CONDITIONS A thesis submitted to the Committee of Graduate Studies in partial fulfillment of the requirements for the Degree of Master of Science in the Faculty of Arts and Science …

    Soil health and soil microbial responses to cash crop management in Ontario

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Ranasinghe, Oshadhi Ruwanthika, Thesis advisor (ths): Thompson, Karen, Degree committee member (dgc): Eimers, Catherine, Degree committee member (dgc): Dang, Huy, Degree granting institution (dgg): Trent University
    Abstract: <p>In Ontario, farmers commonly use a MZ (Maize (Zea mays L.))-SB (Soybean (Glycine max))/WW (Winter wheat (Triticum aestivum)) – CC (mixed cover crop) rotation to maximize economic benefits. This study aimed to investigate the short-term impacts of the crop rotation phases and their associated management practices in this diversified cash crop rotation on soil health and the abundance of… more
    Full Text: SOIL HEALTH AND SOIL MICROBIAL RESPONSES TO CASH CROP MANAGEMENT IN ONTARIO A Thesis Submitted to the Committee on Graduate Studies In Partial Fulfillment of the Requirements for the Degree of Master of Science in the Faculty of Arts and Science TRENT …

    The Characterization of Model Naphthenic Acid Adsorption onto Activated Carbons: Effects of both Textural and Functional Properties

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Roy, Tyler, Thesis advisor (ths): Vreugdenhil, Andrew AV, Degree committee member (dgc): Parnis, Mark MP, Degree committee member (dgc): Shetranjiwalla-Merchant, Shegufta SM, Degree committee member (dgc): Rafferty, Steven SR, Degree granting institution (dgg): Trent University
    Abstract: <p> Naphthenic acids are a major contaminant of concern and a focus of much research around remediation of oil sand process affected waters, OSPW. Using activated carbon adsorbents are an attractive option given their low cost of fabrication and implementation. A deeper evaluation of the effect naphthenic acid structural differences have on uptake affinity is warranted. In this thesis an in… more
    Full Text: The Characterization of Model Naphthenic Acid Adsorption onto Activated Carbons: Effects of both Textural and Functional Properties A Thesis submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Doctor …

    Advancements and Challenges in Ciguatoxin Detection: Developing a High- Resolution Mass Spectrometric Method for the Identification of P-CTX-3B

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Prytulka, Natasha Grace, Thesis advisor (ths): Hintelmann, Holger, Thesis advisor (ths): Stock, Naomi, Degree committee member (dgc): Metcalfe, Chris, Degree granting institution (dgg): Trent University
    Abstract: <p>The detection of ciguatoxins (CTXs) in biological samples is challenging due to their low concentrations, the presence of various congeners, and the absence of standardized methods. This study uses high resolution mass spectrometry (HRMS) with P-CTX-3B as a reference standard. The protonated molecules ([M+H]+) were most prevalent, especially when acetonitrile/water was utilized,… more
    Full Text: Advancements and Challenges in Ciguatoxin Detection: Developing a HighResolution Mass Spectrometric Method for the Identification of P-CTX-3B A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree …

    Movement patterns, food availability, and fungal diets of sympatric flying squirrels in the Kawartha Highlands

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Persad, Rebekah, Thesis advisor (ths): Bowman, Jeff, Degree committee member (dgc): Nol, Erica, Degree committee member (dgc): Davy, Christina, Degree granting institution (dgg): Trent University
    Abstract: <p>Northern flying squirrels (NFS) are mycophagous specialists (fungi-dominated diet) thatmay be displaced with southern flying squirrel (SFS) range expansion, thereby limiting
    fungal dispersal in forest communities. To understand the implications of squirrel
    species turnover on mycophagy, we investigated the home ranges of both flying squirrel
    species who are living in stable sympatry. We… more
    Full Text: Movement patterns, food availability, and fungal diets of sympatric flying squirrels in the Kawartha Highlands A Thesis Submitted to the Committee on Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the …

    Calibration of accelerometer transmitters for estimating field metabolic rates in walleye (Sander vitreus)

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Ritchie, Erin, Thesis advisor (ths): Raby, Graham, Thesis advisor (ths): Brownscombe, Jake, Degree committee member (dgc): West, Sarah, Degree granting institution (dgg): Trent University
    Abstract: <p>The Great Lakes represent nearly a fifth of the global freshwater surface supply, and support culturally, economically, and ecologically important fish species such as Walleye (Sander vitreus). With water temperatures projected to rise by several degrees in the coming century, understanding the energetic impacts on fishes is crucial for effective habitat and fisheries management. I… more
    Full Text: Calibration of accelerometer transmitters for estimating field metabolic rates in walleye (Sander vitreus) A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for the Degree of Master of Science in the …

    Bottom-up pathways for arthropods and forest breeding birds in a southern Ontario forest

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Walters, Benjamin James, Thesis advisor (ths): Nol, Erica, Degree committee member (dgc): Buttle, James M, Degree committee member (dgc): Watmough, Shaun A, Degree granting institution (dgg): Trent University
    Abstract: <p>Long-term avian population declines, particularly for the avian insectivore guild, are a conservation concern. With widespread and continuing population trends, climate change and its negative effects on avian food resources is a plausible cross-species driver. My goal was to evaluate whether bottom-up trophic effects of climate change could be influencing avian populations. I used a… more
    Full Text: Bottom-up pathways for arthropods and forest breeding birds in a southern Ontario forest. A thesis submitted to the Committee on Graduate Studies in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Faculty of Arts and …

    Insights from Dictyostelium: Examining the role of cellular stress in Batten disease

    Year: 2024, 2024
    Member of: Trent University Graduate Thesis Collection
    Name(s): Creator (cre): Thanabalasingam, Aruban, Thesis advisor (ths): Huber, Robert J, Degree committee member (dgc): Yee, Janet, Degree committee member (dgc): Donaldson, Micheal, Degree granting institution (dgg): Trent University
    Abstract: <p>The neuronal ceroid lipofuscinoses (NCLs), commonly known as Batten disease, are a family of fatal neurodegenerative disorders that primarily affect children. Several subtypes of NCLs have been reported, each being caused by a mutation in a distinct ceroid lipofuscinosis neuronal (CLN) gene; this results in aberrant lysosome function and the accumulation of lipoprotein aggregates (known… more
    Full Text: Insights from Dictyostelium: Examining the role of cellular stress in Batten disease A Thesis Submitted to the Committee of Graduate Studies in Partial Fulfillment of the Requirements for Degree of Master of Science in the Faculty of Arts and Science …